Roseola (aka sixth disease) is a disease of children 

• In older children, manifestations limited to:
  • Fever of about 3 days duration
  • Transient rash (exanthem), that follows

Source: 2011/01/roseola-rash.jpg">Prime health channel

• Caused by 2 HHV (human herpesviruses), HHV-6 and HHV-7, aka roseolovirus
• Kids can be congenitally infected with HHV-6 via vertical transmission from mom

• Disease of kids, generally <2yo, although it has been konwn to occur in 18yo's
• Peak presentation is between 3-4yo
• HHV-6 infects over 90% of infants by 2yo
• Congenital infection with HHV-6 occurs in 1% of births

• Measles
• Scarlet fever
• Rubella
• Duke's disease
• Fifth disease